JOB PURPOSE:
Contributes to the research and development of our customers early stage Active Pharmaceutical Ingredients and intermediates projects through the independent performance of experiments with full interpretation of results
JOB RESPONSIBILITIES:
- Conduct laboratory scale experiments in accordance with the work plan with limited direction from the project leader or designate.Contribute to the definition of the work plan through the input and provision of feedback on efficiency or other improvements.
- Document comprehensive, accurate and timely experimental observations in lab books
- Report observations to project leader or designate.Identify potential and actual experiment related problems and propose solutions
- Register and interpret spectra and chromatograms
- Select and perform analytical methods, analyse various samples, interpret results and develop recommendations based on results
- Prepare draft project updates and reports for review by project team leader. May present project updates to internal staff and clients
- Perform the accurate input of hours and comments in TIMS for post project review
- Read and follow R+D Manuals and SOP’s. Contribute and/or lead in the development and revision of R+D Manuals and SOP’s through researching and drafting content
- Participate in opportunities to develop and disseminate a current knowledge of chemistry and technology
- Ensure, and promote, safe and clean lab operations
- Perform departmental tasks such as inventory control, supply ordering, etc;
- Facilitate the training and supervision of co-operative education students and other less experienced staff
- Conduct, report and develop the application of knowledge gained from advanced literature searches
- Liase with cross-functional staff to facilitate project progress. Contribute to identifying potential and actual issues as well as recommending solutions.
- May fulfil project leadership role (e.g. facilitate meeting project objectives, maintain project file, prepare reports, etc;)
- May develop proficiency and expertise in more specialized chemistry techniques or instrumentation
- Perform other duties as assigned
JOB REQUIREMENTS:
- B.Sc. and/or M.Sc. and/or Ph.D. in Chemistry, preferably synthetic organic
- Postgraduate industrial or academic experience in synthetic organic chemistry is an asset. 8-10 years experience at a pharmaceutical and/or fine chemical company is an asset.
- Proven knowledge of organic, synthetic organic chemistry and the methods and techniques in preparative organic chemistry
- Knowledge in process chemistry (e.g. scalability of organic reactions, process safety, selection of solvents, reagents, catalysts and reactions conditions)
- Knowledge, application and interpretation of preparative and analytical chromatography and spectroscopy including the operation of instrumentation such as GC, GC/MS, HPLC and NMR and methods such as IR, UV and MS
- Possess practical skills and knowledge in the interpretation of results obtained from various analytical methods and techniques (e.g. titrations, elemental analysis, KF, ICP, XPRD)
- Ability to resource and effectively utilize chemical information from sources such as chemical abstracts, Organic Synthesis, Organic Reactions and Sci-Finder
- Knowledge of production equipment capabilities in plant and kilo plant environments
- Knowledge of quality systems (e.g. approval and release of materials, documentation, change control, validation of analytical methods and validation of industrial processes) is an asset
- Ability to strictly adhere to safety standards, housekeeping processes and SOP’s
- Software application knowledge and experience (e.g. database, word processor)
Canada Salary Range: CAD80,000.00 - CAD110,000.00/Per Year
